Overview. This figure compares the dominant bioavailability barriers and formulation strategies associated with ral and non-oral drug delivery routes. While oral administration remains the most patient-preferred route, it imposes multiple sequential physiological and biochemical barriers. Non-oral routes bypass some or…
Scientific Background of Vitamin D3 Emulvit‑D is a Vitamin D3 concentrated nanoemulsion engineered for rapid and efficient absorption. This R&D overview summarizes the scientific background of cholecalciferol, vitamin D metabolism, and the technological advantages of nanoemulsion‑based delivery. Cholecalciferol (Vitamin D3)…
Bioavailability is a class-dependent property, governed by distinct limiting mechanisms for small molecules versus biologics. While the formal definition of bioavailability remains unchanged, the dominant barriers, failure modes, and formulation levers differ substantially depending on molecular size, polarity, and susceptibility…
Bioavailability (F) is formally defined as the fraction of an administered dose of an active pharmaceutical ingredient (API) that reaches the systemic circulation in an unchanged form, integrating both absorption efficiency and the impact of first-pass metabolism. For orally administered…
Research & Development Advancing the Science of Delivery Pharcon’s R&D programs focused on solving the challenges associated with poorly absorbable compounds. Our work spans pharmaceutical, nutraceutical, cosmeceutical and hybrid formulations, with an emphasis on improving solubility, permeability, bioavailability of biologically…
